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The search for a pill to help dogs—and humans—live longer

October 16, 2022  |   by Julian L. Mertz  |   No comments
PLUS: More of WIRED's best longreads from this week.

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10.16.22

A photograph by Joe Pugliese of a Great Dane.

The Search for a Pill That Can Help Dogs—and Humans—Live Longer

19-MINUTE READ

Over thousands of years, humans bioengineered wolves into loving, sociable, near-perfect companions. Except for one thing: They leave us far too soon. A Chihuahua can expect roughly 15 years of life; a Great Dane around half that. Celine Halioua—antiaging scientist and pet parent of Wolfie—is building a startup to try to solve that problem. The scientists at her company, called Loyal, are working to hack the biological processes that underlie canine aging and condemn dogs to a relatively short stint on Earth. Her team's got plenty to do before anyone can start slipping anti-senescence pills into food bowls. But if the company's drug targets pan out, there's reason to believe that longevity pills for humans might not be too far behind.

If a pharmacological fountain of youth sounds at all weird—something you'd lump in with freezing your organs and uploading your mind to the cloud—it might be time to update your priors. Numerous companies are chasing commercial antiaging products. Scientists have shown time and again that they can lengthen, or even double, the lifespans of worms, flies, and mice. As WIRED business editor Tom Simonite writes in this week's feature, "in the world of lab animals, life extension is already here." —Sandra Upson | Features Editor

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[New post] Japan: Latest Famitsu review scores

October 16, 2022  |   by Julian L. Mertz  |   No comments
Site logo image Sickr posted: " The latest review scores have come through from Japanese gaming site, Famitsu, and there are six reviews this week. The biggest game is arguably the long-awaited, Return to Monkey Island, which scored 31/40 with the four reviewers giving the point-and-cl" My Nintendo News

Japan: Latest Famitsu review scores

Sickr

Oct 16

The latest review scores have come through from Japanese gaming site, Famitsu, and there are six reviews this week. The biggest game is arguably the long-awaited, Return to Monkey Island, which scored 31/40 with the four reviewers giving the point-and-click adventure game, 7/8/8/8. Here's the full review scores from Famitsu. Via

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