The search for a pill to help dogs—and humans—live longer

PLUS: More of WIRED's best longreads from this week.

View this email in your browser  |  Manage newsletter subscriptions  10.16.22 The Search for a Pill That Can Help Dogs—and Humans—Live Longer 19-MINUTE READ Over thousands of years, humans bioengineered wolves into loving, sociable, near-perfect companions. Except for one thing: They leave us far too soon. A Chihuahua can expect roughly 15 years of life; a Great Dane around half that. Celine Halioua—antiaging scientist and pet parent of Wolfie—is building a startup to try to solve that problem. The scientists at her company, called Loyal, are working to hack the biological processes that underlie canine aging and condemn dogs to a relatively short stint on Earth. Her team's got plenty to do before anyone can start slipping anti-senescence pills into food bowls. But if the company's drug targets pan out, there's reason to believe that longevity pills for humans might not be too far behind. If a pharmacological fountain of youth sounds at all weird—something you'd lump in with freezing your organs and uploading your mind to the cloud—it might be time to update your priors. Numerous companies are chasing commercial antiaging products. Scientists have shown time and again that they can lengthen, or even double, the lifespans of worms, flies, and mice. As WIRED business editor Tom Simonite writes in this week's feature, "in the world of lab animals, life extension is already here." —Sandra Upson | Features Editor READ THE FULL STORY You Might Also Like ... Why Therapy Is Broken BY ELEANOR CUMMINS | 7-MINUTE READ Everyone is telling one another to "get help," but few acknowledge that the practice is often flawed. The Unlikely Cure for Burnout? A Second Job BY FADEKE ADEGBUYI | 6-MINUTE READ "Overemployment" sounds like more of the same old grind, but its underlying philosophy is critical of work. What It Means to 'Feel Normal' Online BY TUNG-HUI HU | 7-MINUTE READ A personalized, authentic experience is an unquestioned building block of digital infrastructure. But what does that really involve? The US Needs to Recognize Intimate Privacy as a Civil Right BY DANIELLE KEATS CITRON | 7-MINUTE READ Digital privacy invasion isn't just a consumer protection issue. It's inextricably linked to equality, with urgent implications for women and minorities. The Signal for Help I Created Went Viral. Now It Could Be Misused BY ANDREA GUNRAJ | 4-MINUTE READ Well-meaning efforts to integrate the hand signal with digital technology could expose vulnerable people to detection and escalated violence. AI Shouldn't Compete With Workers—It Should Supercharge Them BY CLIVE THOMPSON | 5-MINUTE READ The economy could get a boost if machine learning engineers switched from copying human abilities to augmenting them. GET WIRED Get 1 year of WIRED for less than $1 per month. That includes Steven Levy's exclusive newsletter and a free tote! Subscribe now. Have questions or comments? Reply to this email.   This email was sent to you by WIRED. To ensure delivery to your inbox (not bulk or junk folders), please add our email address, wired@newsletters.wired.com, to your address book.   View our Privacy Policy Unsubscribe or manage your newsletter subscriptions